JOB SUMMARY

The University of Connecticut Proteomics and Metabolomics Facility (UConn PMF, https://proteomics.uconn.edu) is hiring a Facilities Scientist 2 to assist the Facility Director with quantitative proteomics analysis using advanced mass spectrometry instrumentation and leading bioinformatics software. The PMF opened in 2017 as the University of Connecticut’s first proteomics-focused and full service mass spectrometry core facility, and is housed administratively within the Center for Open Research Resources and Equipment (https://core.uconn.edu). UConn PMF in Storrs has outstanding instrumentation (2 Waters TOFs, 2 Thermo Scientific Orbitraps, and a Bruker timsTOF HT) and is expanding its footprint to the UConn Health medical research campus (Farmington, CT) in Summer 2025 with a brand new Bruker timsTOF Ultra 2 mass spectrometer.  UConn PMF exists to provide fully customized analysis to more than 200 faculty across multiple UConn campuses and at other regional academic and industry research institutions. This position will be a full-time appointment and will provide a unique opportunity to work in a rapidly growing and highly productive core facility at a large research university currently ranked in the top 25 of all public universities in the U.S.

MINIMUM QUALIFICATIONS

1. Master’s degree in chemistry, biochemistry, analytical chemistry, or related field with at least 3 years of experience, OR Ph.D. degree in a similarly relevant field, with demonstrated experience implementing high resolution mass spectrometry for the analysis of proteins and peptides, and familiarity with operation, maintaining, and troubleshooting high resolution mass spectrometer and nanoflow ultra-high performance liquid chromatography systems.
2. Publication history that demonstrates successful application of state-of-the-art mass spectrometry for label-free and/or label-based (e.g. Tandem Mass Tags, iTRAQ, SILAC) quantitative proteomics.
3. Demonstrated experience using common proteomics software platforms for peptide/protein identification and quantification such as Spectronaut, MaxQuant/Andromeda, Proteome Discoverer, Byonic, and/or Scaffold Q+S.
4. Demonstrated mastery of sample preparation techniques for downstream proteomics analysis such as in-gel/in-solution digestions, co-immunoprecipitations, and processing of whole cell lysates or tissue homogenates for bottom-up proteomics.
5. Demonstrated clear and effective communication skills while communicating with researchers of varied scientific backgrounds, specifically regarding analytical techniques and informatics methods.
6. Experience working in a highly collaborative environment that emphasizes comprehensive analysis and one-on-one consultations with researchers.

PREFERRED QUALIFICATIONS

1. Experience with extensive collaborative projects or experience in a core facility setting.
2. Experience using Bruker timsTOF instrumentation for low input proteomic analysis utilizing DDA-PASEF and DIA-PASEF acquisition methods.
3. Experience with untargeted metabolomics workflows, including sample preparation and analysis using TOF instrumentation and small molecule identification using Progenesis QI, XCMS, and/or other programs.

APPOINTMENT TERMS

This is a full-time, 12-month, non-tenure-track position with an anticipated start date in September 2025. Salary will be commensurate with qualifications and experience. Other rights, terms, and conditions of employment are contained in the collective bargaining agreement between the University of Connecticut and the American Association of University Professors UConn Chapter (AAUP).

The University offers a competitive salary, and outstanding benefits, including employee and dependent tuition waivers at UConn, and a highly desirable work environment. For additional information regarding benefits, please visit hr.uconn.edu and explore the sections under the Benefits & Leaves and Engagement & Learning headers.

TERMS AND CONDITIONS OF EMPLOYMENT

Employment of the successful candidate is contingent upon the successful completion of a pre-employment criminal background check.

TO APPLY

Please apply online at https://hr.uconn.edu/jobs, Faculty and Staff Positions, Search #499108 and submit the following application materials: resume, cover letter, and contact information for three (3) professional references.

Questions regarding this search should be addressed to Dr. Jeremy Balsbaugh, Director of COR²E and PMF (jeremy.balsbaugh@uconn.edu).

This job posting is scheduled to be removed at 11:55 p.m. Eastern time on August 8, 2025. 

All employees are subject to adherence to the State Code of Ethics which may be found at http://www.ct.gov/ethics/site/default.asp.

All members of the University of Connecticut are expected to exhibit appreciation of, and contribute to, an inclusive, respectful, and diverse environment for the University community.

The University of Connecticut aspires to create a community built on collaboration and belonging and has actively sought to create an inclusive culture within the workforce. The success of the University is dependent on the willingness of our diverse employee and student populations to share their rich perspectives and backgrounds in a respectful manner. This makes it essential for each member of our community to feel secure and welcomed and to thoroughly understand and believe that their ideas are respected by all. We strongly respect each individual employee’s unique experiences and perspectives and encourage all members of the community to do the same. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.

The University of Connecticut is an AA/EEO Employer.